500FG

The cohort consists of 534 healthy individuals, of whom 44% are male and 56% are female, all of Western-European genetic background.

200FG

The cohort comprises 197 healthy adults working as foresters from the ‘Geldersch Landschap’, ‘Hoge Veluwe’, ‘Twickel’, and ‘Kroondomein het Loo’ in the Netherlands. These individuals were between 23 and 73 years old, and 77% were male, and 23% female.

2000HIV

This study consists of 1895 participants. The majority of participants were cis-male, and of white ethnical ancestry.

BCG PRIME

This is a randomized, controlled, multicenter trial that included 6112 immunologically vulnerable individuals aged over 60.

300BCG

The aim of this project is to elucidate the host and environmental factors that influence the magnitude ofthe individual trained immunity responses to BCG vaccination using a systems biology approach. The Bacillus Calmette-Guérin (BCG) vaccine not only protects against infection…

INFLUENZA-SHINGRIX

Distinct protective mechanisms of influenza (Fluarix) and shingles (Shingrix) vaccines in 74 young (18-35) and 58 older (60+) individuals.

300OB

Role of inflammation and gut microbiota as drivers of cardiovascular disease in 302 overweight or obese individuals.

300DM

Role of inflammation and gut microbiome as drivers of diabetes complications in 243 patients with type I diabetes.

HINT

Role of uric acid in rheumatic and cardiovascular diseases in 193 gout patients, 154 individuals with asymptomatic hyperuricemia, and 215 healthy controls from Romania.

200-INDIA

TransInf

Effect of diet on immune and vaccine responses in people living with overweight/obesity and non-obese controls in Tanzania.

ImmunAgeD

ImmunAgeD includes 120 subjects participating in the cross-sectional substudy, and an estimated 500 patients, representing the cohort explored longitudinally, formerly enrolled as healthy controls in the FUSE study.

300-Tanzania

Interaction between the genome, microbiome, and immune responses in 323 healthy individuals from Tanzania.